Impact of Diabetes on Fracture Healing
نویسندگان
چکیده
Department of Periodontics, University of Pennsylvania, Philadelphia, PA, USA Department of Oral Basic & Clinical Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia Department of Orthopedics, University of Medicine and Dentistry of New JerseydGraduate School of Biomedical Sciences, Newark, NJ, USA Department of Biochemistry and Molecular Biology, University of Medicine and Dentistry of New JerseydNew Jersey Medical School, Newark, NJ, USA Department of Orthopaedics, University of Medicine & Dentistry of New JerseydNew Jersey Medical School, Newark, NJ, USA
منابع مشابه
The Impact of Type 2 Diabetes on Bone Fracture Healing
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease known by the presence of elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a very high socioeconomic impact on public health. Many are the complications caused by this chronic disorder, including a negative impact on the cardiovascular system, kidneys, eyes, muscle, blood vessels, and nervous sys...
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BACKGROUND AND PURPOSE A variety of risk factors have been hypothesized to contribute to the development of fracture-healing complications; however, population-based estimates of the strength of these risk factors are limited. In this case-control study, we evaluated patient-related risk factors for fracture-healing complications. METHODS Using the United Kingdom General Practice Research Dat...
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Chemokines are thought to play an important role in several aspects of bone metabolism including the recruitment of leukocytes and the formation of osteoclasts. We investigated the impact of diabetes on chemokine expression in normal and diabetic fracture healing. Fracture of the femur was performed in streptozotocin-induced diabetic and matched normoglycemic control mice. Microarray analysis w...
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The advent of improved glucose control with insulin and oral medications has allowed for the diabetic population to live longer and healthier lives. Unfortunately diabetes remains a worldwide epidemic with multiple health implications. Specifically, its affects upon fracture healing have been well studied and shown to have negative effects on bone mineral density, biomechanical integrity, and f...
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PURPOSE OF THE STUDY Diabetics may have an increased fracture risk, depending on disease duration, quality of metabolic adjustment and extent of comorbidities, and on an increased tendency to fall. The aim of this retrospective one-centre study consisted in detecting differences in fracture healing between patients with and without diabetes mellitus. Data of patients with the most common fractu...
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